I don't think anyone's expecting a sit-com, but I think there is a desire to stop being told someone or something is funny and actually be shown the funny... or stop talking about it altogether. Personally I'd love the show to be darker - give everyone a drug problem or a personality disorder, comedians aren't necessarily that funny to talk to but they're usually a little off.
It's so hard to know what will become of all these shows. I've seen pilots that I've loved that have turned into awful series and craptacular pilots become fabulous shows. There are series that don't come into their own until the second season and others that should have quit after the first. Right now I'm excited about Heroes because it surprised me while Studio 60 did not, but yesterday's squee can easily become tomorrow's meh. I'll definitely be watching both shows, it's nice to have options for a change. Those were a couple lean years after AtS.
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It's so hard to know what will become of all these shows. I've seen pilots that I've loved that have turned into awful series and craptacular pilots become fabulous shows. There are series that don't come into their own until the second season and others that should have quit after the first. Right now I'm excited about Heroes because it surprised me while Studio 60 did not, but yesterday's squee can easily become tomorrow's meh. I'll definitely be watching both shows, it's nice to have options for a change. Those were a couple lean years after AtS.